Pharmaceutical Chemicals
Isosorbide Dinitrate CAS 87-33-2 as Coronary Vasodilator (jerryzhang001@chembj.com)
87-33-2
Description
Isosorbide Dinitrate CAS 87-33-2 as Coronary Vasodilator
Product Name: Isosorbide dinitrate;
Synonyms: 1,4:3,6-dianhydro-,dinitrate,d-glucito;1,4:3,6-dianhydro-d-glucitodinitrate;1,4:3,6-dianhydrosorbitol2,5-dinitrate;cardis;carvanil;carvasin;cedocard;claodical;
CAS: 87-33-2;
MF: C6H8N2O8;
MW: 236.14;
EINECS: 201-740-9;
Product Categories: chiral;Nitric Oxide Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;
Melting point: 700℃;
storage temp.: -20℃ Freezer;
Chemical Properties: white to light yellow crystal powde;
Usage: Coronary vasodilator;
Description:
Isosorbide dinitrate (ISDN) is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine in black people. It is taken by mouth or under the tongue.
Common side effects include headache, lightheadedness with standing, and blurred vision. Severe side effects include low blood pressure. It is unclear if use in pregnancy is safe for the baby. It should not be used together with medications within the sildenafil family. ISDN is in the nitrate family of medications and works by dilating blood vessels.
Isosorbide dinitrate was first written about in 1939. It is on the World Health Organization& acute;s List of Essential Medicines, the most effective and safe medicines needed in a health system.ISDN is available as a generic medication.The wholesale cost in the developing world is about 6.36 USD a month. In the United States it costs less than 25 USD per month. A long acting form exists.
Usage:
It is used for angina, in addition to other medications for congestive heart failure, and for esophageal spasms.
Long-acting nitrates can be more useful as they are generally more effective and stable in the short term.
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