Pharmaceutical Chemicals

Beijing Nuoxuan Kangle Biological Science and Technology Co.ltd. is a leading and professional manufacturer and supplier in anabolic steroids, body-building supplements, pharmaceutical intermediates and Cosmetic raw materials. We are situated in Changping district, Beijing City, China.

Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1).[1][2] It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1).[2] The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.[1][2] As a result, it is approximately three times more potent than IGF-1,[3] and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours).[4]

Get Quote

Send Inquiry by feedback form learn more about product detail, price, etc
*Your email address will not be published. Required fields are marked.

Submit