Medicine & Health Products
Description
Sildenafil(CAS NO.:139755-83-2)
Trade names:Viagra,Revatio
CAS:139755-83-2
MF:C22H30N6O4S
MW:474.58
Characteristics: white or off-white crystal powder, odorless, bitter, can& acute; t melt in water and ethanol
Key words:Sildenafil Viagra Revatio 139755-83-2 male sex enhancer ED erectile dysfunction Pulmonary hypertension
Medical uses:
(1)Sexual dysfunction
The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction including for those with diabetes mellitus.
(2)Pulmonary hypertension
As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension. It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. This, in turn, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the United States Food and Drug Administration (FDA), and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-mg tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.
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Hongkong Yuancheng Saichuang Technology Co., Ltd
Steroid powders,Pharmaceutical intermediates,Healthcare products,Food addictives,Flavours and fragrances,Plant&Animal Extract
Address: No. 496 Zhongshan Road, Wuchang District,
Wuhan, Hubei
China, 430000
Tel: 86-027-50756211
Fax: 86-027-68886696
