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Penis Enlargement Steroids Powder Sildenafil Citrate For Erectile Dysfunction 171599-83-0
171599-83-0
Description
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Product Name | Sildenafil Citrate |
Chemical Name | Sildenafil; Viagra |
CAS Number | 171599-83-0 |
Molecular Formula | C28H38N6O11S |
Molecular Weight | 666.7 |
Molecular structure | |
Melting Point | 187-189°C |
Purity | 99.5% ? |
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Description:
VIAGRA (sildenafil citrate), an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/mL in water.
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VIAGRA is formulated as blue, film-coated rounded-diamond-shaped tablets equivalent to 25 mg, 50 mg and 100 mg of sildenafil for oral administration. In addition to the active ingredient, sildenafil citrate, each tablet contains the following inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose, triacetin, and FD & C Blue #2 aluminum lake.
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Viagra (sildenafil) relaxes muscles found in the walls of blood vessels and increases blood flow to particular areas of the body,used to treat erectile dysfunction (impotence) in men. Another brand of sildenafil is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.
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Mechanism Of Action
The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
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Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.
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Viagra dosing information:
Usual Adult Dose for Erectile Dysfunction:
Initial dose: 50 mg orally once a day, as needed, 1 hour prior to sexual activity
Maintenance: 25 to 100 mg orally once a day, as needed, 1 hour prior to sexual activity
Comments: This drug may be taken anywhere from 30 minutes to 4 hours before sexual activity.
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Usual Geriatric Dose for Erectile Dysfunction:
Initial dose: 25 mg orally once a day 1 hour prior to sexual activity
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Side effects:
Dizziness, headache, flushing, or stomach upset may occur. Vision changes such as increased sensitivity to light, blurred vision, or trouble telling blue and green colors apart may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
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Address: Mingzhi Street Long hua,
Shenzhen, Guangdong
China, 518000
Tel: 86-155-27046746
Fax: 86-155-27046746
