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PT141 Polypeptide Hormones Bremelanotide Peptide Powder PT-141 with 10mg

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Description

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PT141 Polypeptide Hormones Bremelanotide Peptide Powder PT-141 with 10mg/vial

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PT-141,Bremelanotide, 10mg/vial

Molecular Formula: C50H68N14O10
Molecular Weight: 1025.16
CAS NO:189691-06-3
Sequence:H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
1.Appearance White powder White powder
2 Solubility Soluble in water and 1% acetic acid Conforms
3 Specifical Optical Rotation -50°~-60°(c=1,1%HAc) -55.65°
4 Peptide Purity (By HPLC) ≥ 98.0% by area integration 99.67%

PT-141(Bremelanotide)is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction. The mechanism of action of PT-141 (Bremelanotide)may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system.

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Description:

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PT-141, commonly known as PT141 or Bremelanotide, is a synthetic heptapeptide analogue of the naturally occuring alpha-Melanocyte stimulating hormone (α-MSH) that is currently being studied for its numerous theoretical therapeutic applications. Alpha-MSH has potent influence over lipid metabolism, appetite, and sexual libido. PT-141 Bremelanotide, a metabolite of its predecessor Melanotan II, has the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH and a molecular weight of 1025.2 Dalton. In initial testing, Melanotan II did induce melanogenesis, but additionally caused sexual arousal and spontaneous erections as unexpected side effects in nine out of the ten original male volunteer test subjects. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Resultantly, PT-141 has been shown in studies to exhibit libido-enhancing effects by activating melanocortin receptors. PT 141 has been researched extensively for its possible treatment of male sexual dysfunction (erectile dysfunction or impotence), female sexual dysfunction (sexual arousal disorder), hemorrhagic shock and reperfusion injury.

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PT-141 functions by activating the melanocortin 1 receptor and MC4R namely. Bremelanotide originally was tested for nasal spray delivery but was discontinued after concerns about side effects. Bremelanotide PT141, as Melanotan II, may cause spontaneous arousal enhancing effect. Unlike other supplements, pt 141 results do not act on the vascular body, but directly increases desires through the nervous system.

Bremelanotide PT-141 Peptide Synthesis Information

Our PT141 delivers 99% purity ratings, HPLC quality tested PT-141 10MG. Furthermore, bremelanotide triggers the melanocortin system to cascade variably to melanocortin receptors, more than PDE5 meds. Small-structure biologic melanocortin peptides molecule remains potent during shipping as well as in storage. Melanotan 2 and PT141 melanocortins do not require cold shipping to remain effective. Products stay potent and should not expire until years later when stored properly in the fridge or freezer.

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Applications:
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PT-141 is a synthetic amino acid protein discovered during clinical trials using the Melanotan 2 for sunless tanning, photo-protection results from melanotans. Participants were documented as having experienced aphrodisiac reactions, leading to the further developmentPT-141. The melanocortin system targets receptors associated with desire through the melanocyte stimulating hormone paths that cross the blood-brain-barrier. Potentially the powerful sex-drug results feeling an aphrodisiac experience amplifying arousal pt141 reviews have shown the ability to increase libido effects of both men and women.

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