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Beclometasone Dipropionate

5534-09-8

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Description

Beclometasone Dipropionate
product Name: Beclometasone Dipropionate
CAS Registry Number: 5534-09-8
Packaging: 1kg/Aluminum foil bag
Quality Standards: USP31
Molecular Formula: C28H37ClO7
Molecular Weight: 521.05
EINECS: 226-886-0
Appearance: It is a white to creamy-white, odorless powder which is very slightly soluble in water, very soluble in chloroform, and freely soluble in acetone and in ethanol.
Usage: Beclometasone dipropionate ( INN modified) or beclomethasone dipropionate ( USAN , former BAN ) is a potent glucocorticoid steroid. It is a prodrug of the free form, beclometasone (INN). In the form of an inhaler (eg Clenil, Qvar), a wide number of brands of which are available, it is used for the prophylaxis of asthma. As a nasal spray (eg Beconase, alanase, Vancenase), it is used for the treatment of rhinitis (eg hay fever ) and sinusitis .
As a cream or ointment (trade name Propaderm), it is used to treat severe inflammatory skin disorders (e.g. eczema) unresponsive to less potent steroids, but is generally avoided in the treatment of psoriasis due to the risk of rebound on withdrawal.
It is also licensed to treat ulcerative colitis in conjunction with doses of 5-aminosalicylates in the United Kingdom in the form of a gastric acid-resistant, periodic release tablet marketed under the brand name Clipper.

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