Biochemical
Description
Cilostazol CAS 73963-72-1 Antibacterial 99% White Powder
Basic information:
Cilostazol
Synonyms:
13013;OPC 21
CAS: 73963-72-1
MF: C20H27N5O2
MW: 369.46
Purity: 99%
White Powder
Categories:
Active-Pharmaceutical-Ingredients;Intermediates&Fine-Chemicals;Pharmaceuticals;API& acute;s;inhibitor;Cardiovascular APIs
Product description:
Cilostazol is commonly used clinically anti-platelet and anti-clotting drugs. It belongs to a phosphodiesterase inhibitor and can inhibit the activity of phosphodiesterase of platelet and smooth muscle cells, leading to increase of the AMP concentration in platelets and vascular smooth muscle. It can significantly inhibit the platelet aggregation induced by various kinds of aggregation inducers, and can cause the dissociation of the aggregates. Its major metabolite, epoxide has a three to four fold activity of the prototype drug. It has significant antithrombotic effect on the brain circulation and peripheral circulatory disturbance caused by collagen, ADP, arachidonic acid and sodium laurate. Artery injection of this product can increase the blood flow rate with the strongest effect on the peripheral blood vessels but the weakest effect on the cerebral blood vessels.
Product Application:
It can be used to alleviate the ischemic symptom such as ulcers, limb pain, cold sensation and intermittent claudication caused by chronic arterial occlusive disease. It can also be applied to the adjuvant treatment of atherosclerosis, arteritis, thromboangiitis obliterans, diabetes-induced ischemia of extremity and takayasu arteritis. Cilostazol also be used as a complementary therapy after surgical treatment to help alleviate the symptoms, improve the circulation
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Nanjing Bangnuo Biotechnology Co., Ltd.
chemcical
Address: Tianqinwan Garden NO.1008 Ssangyong Avenue , Jiangning District,
nanjing, jiangsu
China, 211100
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