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Description
ABT-737 is a pan-Bcl-2 inhibitor that has a wide range of single-agent activity against acute lymphoblastic leukemia (ALL) cell lines and xenografts. Increased expression of the Bcl-2 family of proteins in cancers has been associated with chemotherapy resistance, inhibiting Bcl-2 or Bcl-XL overexpression could potentially induce apoptosis in cancer cells while having minimal effects on normal cells.
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ChemScene, LLC
ChemScene Pharmaceutical chemical
Address: 11 Deer Park Drive, Suite 102A, Monmouth Junction, NJ 08852,
jersey, new jersey
United States, 07097
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