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Peptide hormone CJC-1295 with DAC for anti aging

863288-34-0

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Description

CJC-1295 with DAC

EMAIL: cgf at chembj dot com
Skype: cgf@chembj.com
Whatsapp: +8615564141272

Synonyms : CJC1295/DAC, CJC-1295 with dac, CJC 1295
CAS NO: 863288-34-0
Molecular Formula : C165H269N47O46
Molecular Weight : 3647.19
Appearance: White Powder
Purity: 98.71%
Certifiation: GBP, ISO9001, FDA
Standard: Enterprise standard
Source: Chemical Synthesis
Storage: Lyophilized CJC-1295 W/ DAC is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting CJC-1295 W/ DAC should be refrigerated at temperatures not to exceed 36 F.

Description:

CJC-1295 is a derivative of human GH-releasing factor1-29(HGRF1-29). HGRF1-29 is a naturally occurring peptide that is actually a truncated form of a larger peptide that binds to the growth hormone secretagogue receptor (GHS-R) and causes the release of growth hormone. CJC-1295 has four amino acids substituted in its chain that result in strong binding to serum albumin and prolong its half-life in the body.

Because of the way CJC-1295 is engineered its half life has been extended from ~7 minutes to greater than 7 days!. This is convenient as it means the product only needs to be injected 1-2 times per week for continuously elevated levels of Human Growth Hormone (HGH) and IGF-1. A single subcutaneous (sc) injection results in measurable quantities of CJC-1295 in the blood for up to 13 days. Additionally, a single dose of 60 ug/kg of CJC-1295 results in elevated levels of growth hormone (125%) while the pulsatile secretion of GH is maintained. Furthermore, 60 ug/kg of CJC-1295 elevated IGF-1 levels to the upper limit of normal. A dose of 30 ug/kg of CJC-1295 given weekly maintained its response with no evidence of desensitization.

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