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36791-04-5 Pharmaceutical Raw Materials Ribavirin For Antbiotic / Antimicrobial Agents

MEDICINE RAW MATERIAL

Description

36791-04-5 Pharmaceutical Raw Materials Ribavirin For Antbiotic / Antimicrobial Agents

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Products details

the other name is 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide

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Theory and Application

Ribavirin is active against a number of DNA and RNAviruses. It is a member of the nucleoside antimetabolite drugs that interfere with duplication of viral genetic material. Ribavirin is active against influenzas, flaviviruses, and agents of many viral hemorrhagic fevers.

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Ribavirin is the only known treatment for a variety of viral hemorrhagic fevers, including Lassa fever, Crimean-Congo hemorrhagic fever,Venezuelan hemorrhagic fever, and Hantavirus infection, although data regarding these infections are scarce and the drug might be effective only in early stages.

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Specifications:

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Product Name | ribavirin |
Density | 2.08g/cm3 |
Melting point | 174-176℃ |
Boiling point | 639.8°C at 760 mmHg |
Refractive index | 1.823 |
Flash point | 340.7°C |
Water soluility | >=10 g/100 mL at 19℃ |
Vapour Pressur | 3.03E-17mmHg at 25°C |
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Theory and Application

Ribavirin is active against a number of DNA and RNAviruses. It is a member of the nucleoside antimetabolite drugs that interfere with duplication of viral genetic material. Ribavirin is active against influenzas, flaviviruses, and agents of many viral hemorrhagic fevers.

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Ribavirin is the only known treatment for a variety of viral hemorrhagic fevers, including Lassa fever, Crimean-Congo hemorrhagic fever,Venezuelan hemorrhagic fever, and Hantavirus infection, although data regarding these infections are scarce and the drug might be effective only in early stages.

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Function:

Ribavirin is an anti-viral drug indicated for severe RSV infection (individually), hepatitis C infection (used in conjunction with peginterferon alfa-2b or peginterferon alfa-2a) and other viral infections. Ribavirin is a prodrug, which when metabolised resembles purine RNA nucleotides. In this form it interferes with RNA metabolism required for viral replication. How it exactly affects viral replication is unknown; many mechanisms have been proposed for this (see Mechanisms of Action, below) but none of these has been proven to date. Multiple mechanisms may be responsible for its actions.

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Chemical structure:
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