Vision Care Products
Description
Lidocaine Local Anesthetic Drugs Lidocaine Hydrochloride for Pure Topical ?
Product?Details:?
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Product name: Lidocaine Hydrochloride
Other name: Lidocaine HCL, Lidocaine, Lidocaine Base
Cas: 73-78-9
MF: C14H23ClN2O
MW: 270.7982
Melting point: 350.8° C at 760 mmHg
Usage: Local anesthetics, antiarrhythmic drugs, used for a variety of anesthesia and rapid ventricular arrhythmia
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Description:
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Lidocaine may be absorbed following topical administration to mucous membranes, its rate and extent of absorption depending upon concentration and total dose administered, the specific site of application, and duration of exposure. In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. Lidocaine is also well-absorbed from the gastrointestinal tract, but little intact drug may appear in the circulation because of biotransformation in the liver.
Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide.
The plasma binding of lidocaine is dependent on drug concentration, and the fraction bound decreases with increasing concentration. At concentrations of 1 to 4 mcg of free base per mL, 60 to 80 percent of lidocaine is protein bound. Binding is also dependent on the plasma concentration of the alpha-1-acid glycoprotein.
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Specifications?:
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Analysis Report
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Product?name | Lidocaine?Hydrochloride |
Appearance | White?crystalline?powder |
Assay?(C13H20N2O2·HCl) | 99.0%?to?101.0% | 99.75% |
Solution?Appearance | Clear?and?colorless | Confirm |
PH?Value | 4.0~5.5 | 4.65 |
Related?impurities | impurity?A:≤0.01% | 0.002% |
? | Single?unspecified?impurity:?≤0.1% | 0.02% |
? | Total?impurity:?≤0.5% | 0.20% |
Heavy?Metal | ≤5ppm | ＜5ppm |
Water | 5.5%~7% | 6.13% |
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Competitive?Advantage:
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2. our products have exported to US, Brazil, Canada, Germany, UK, Spain, France, Norway, Romania, Italy, Australia and many other areas. We build long-term cooperation relationship with all of the customers. 3. Could be shipped out within 24 hours after received the payment. 4. High quality, best price, first-class service, high successful delivery rate.
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Hubei Holy Biological Co., Ltd.
Anabolic Steroid Powder,Raw Steroid Powders,Testosterone Steroid Hormone
Address: 202#,Huaxia Science and Technology Industrial Park,Pingdi,Longgang District, Shenzhen City, Guangdong,China,
Shenzhen, Guangdong
China, 518000
Tel: 86-755-86849546
Fax: 86-755-86849537
