Pharmaceutical Chemicals
Description
Coluracetam
Keywords:nootropics Piracetam,Aniracetam,Pramiracetam,Oxiracetam, Coluracetam,Phenylpiracetam smart drugs Piracetam,Aniracetam, Pramiracetam,Oxiracetam,Coluracetam,Phenylpiracetam hot sale nootropics
CAS No:135463-81-9
Purity:99%
Appearance:white crystalline powder
Package:1kg/bag.
Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer& acute;s disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a & quot;Qualifying Therapeutic Discovery Program Grant& quot; by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.
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